Custom Peptides
Cayman Chemical NDesethylamIodaronhydroch 10mg
the major CYP3A4 metabolite of amiodarone; used as an analytical reference standard for monitoring clinical efficacy of amiodarone in plasma samples
Cayman Chemical N NDImethylcathInonhydroc 10mg
A psychotropic compound of the phenethylamine and cathinone classes; slightly less potent than methcathinone and essentially equipotent with cathinone, in behavioral studies involving rats; intended for forensic purposes
Cayman Chemical O-ArachIdonyl EthnolamIn 10mg
A constituent of human and rat brain in which the ethanolamine moiety is attached “backwards”, as an ester rather than as an amide as in AEA; has mixed agonist/antagonist activity at the CB1 receptor
Cayman Chemical ArachIdonyl GlycIn 10mg
Produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA; has analgesic activities in whole animal experiments, yet is a very poor ligand for the CB1 receptor
Cayman Chemical DETA Nonate 10mg
DETA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 20 hours and 56 hours at 37°C and 22-25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound.{1190,5437}
Cayman Chemical ZINC00881524 10mg
A ROCK inhibitor; decreases levels of ROCK1 in T47D and CAMA-1 breast cancer cells; decreases proliferation of T47D and CAMA-1 cells when used in combination with CNN1 knockdown
Cayman Chemical SynthetIc Curzeren 10mg
A sesquiterpene with diverse biological activities; scavenges DPPH radicals in a cell-free assay at 3.36 UG/L with a synergistic effect when used in combination with eucalyptol; active against F. graminearum at 0.5 mg/ml; inhibits the proliferation of SK-MEL-19 melanoma cells (IC50 = 5.17 UG/ml), as well as AGP-01 gastric and HCT116 colon cancer cells (IC50s = 8.04 and 9.18 UG/ml, respectively) and MRC-5 non-cancerous human fibroblasts (IC50 = 11.45 UG/ml); induces apoptosis in, and decreases migration of, SK-MEL-19 cells at 5 and 10 µM; reduces tumor weight in an SPC-A1 mouse xenograft model at 135 mg/kg
Cayman Chemical 4NItrophenyl aLrhamnopyrn 10mg
A colorimetric naringinase substrate; upon hydrolysis by the α-rhamnosidase subunit of naringinase, 4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure of naringinase α-rhamnosidase activity; has been used in the detection of naringinase α-rhamnosidase activity in various bacteria
Cayman Chemical Alclometason DIpropIonate 10mg
A corticosteroid; reduces cutaneous anaphylaxis reactions induced by tuberculin or albumin in mice when administered topically (20 μl of a 0.1% solution); inhibits androgen-dependent cytochrome P450 activity and the O-depropylation activity of 7-alkoxy-coumarin O-dealkylase in a dose-dependent manner in male rats; has no effect on hepatic drug metabolism in female rats or mice of both sexes
Cayman Chemical RavIdasvIrhydrochlorIde 10mg
An NS5A inhibitor; inhibits HCV replication in Huh7 replicon cells containing NS5A from the HCV genotypes 1a, -1b, and 3a (EC50s = 0.12, 0.01, and 1.14 nM, respectively)
Cayman Chemical Gunylyl ImIdodIphosphATlI 10mg
A nonhydrolyzable GTP analog that binds to and irreversibly activates G proteins; potently stimulates adenylate cyclase
Cayman Chemical DSmethyl MIrtazapInhydroc 10mg
A metabolite of mirtazapine; formed from mirtazapine by CYP3A4
Cayman Chemical QuasIa amara QuasIn 10mg
A quassinoid with diverse biological activities; active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50 = 0.15 µM for both); has antifeedant and insecticidal activity against the diamondback moth when applied to dietary cabbage leaf discs at 16, 31.9, or 63.7 UG/cm2; increases viability of SH-SY5Y cells in a model of hydrogen peroxide-induced neuronal injury at 25, 50, or 100 µM
Cayman Chemical U-ContoxInacetate 10mg
A conotoxin and an inhibitor of Nav1.4 receptors; inhibits Nav1.4 in HEK293 cells (IC50 = 2.3 nM for the rat channel); inhibits rat Nav1.2 channels in HEK293 cells at 500 nM and is an antagonist of a7 nAChRs and a4ß2 and a3ß2 subunit-containing nAChRs in Xenopus oocytes expressing the human receptors (IC50s = 22, 2.9, and 0.45 µM, respectively); reduces global nerve action potential in isolated mouse sciatic nerves in a concentration-dependent manner; inhibits contraction in isolated mouse hemidiaphragm muscles (IC50 = 46 nM)